Understanding the Serious Risks of Opioid Use: A Guide for Patients
Understanding the Serious Risks of Opioid Use: A Guide for Patients

At Yarmouth Medical Center, we are dedicated to your health and safety. While opioid medications can be effective for managing certain types of pain, they also carry significant risks that must be carefully considered.(U.S. Food and Drug Administration)
What Are Opioids?
Opioids are a class of medications commonly prescribed to relieve moderate to severe pain. They work by binding to specific receptors in the brain and spinal cord, reducing the perception of pain. Examples include oxycodone, hydrocodone, morphine, and fentanyl.
Serious Risks Associated with Opioid Use
- Addiction and Dependence: Opioids have a high potential for addiction. Even when taken as prescribed, prolonged use can lead to physical dependence, where the body adapts to the drug, and withdrawal symptoms occur if the medication is stopped.
- Overdose: Taking too much of an opioid can slow or stop breathing, leading to death. The risk increases when opioids are combined with other substances like alcohol, benzodiazepines, or certain antidepressants. (dentistry.ky.gov)
- Side Effects: Common side effects include drowsiness, constipation, nausea, and confusion. In older adults, opioids can increase the risk of falls and fractures. (Wikipedia)
- Hormonal Imbalances: Long-term opioid use can disrupt hormonal systems, leading to issues like decreased libido, infertility, and osteoporosis. (Wikipedia)
- Impact on Mental Health: Opioid use can exacerbate mental health conditions, leading to increased anxiety, depression, and in some cases, suicidal thoughts.(Wikipedia)
Safe Use and Alternatives
- Follow Prescriptions Carefully: Take opioids exactly as prescribed. Do not adjust the dose or frequency without consulting your healthcare provider.
- Discuss Alternatives: Ask about non-opioid pain management options, such as physical therapy, acupuncture, or non-opioid medications.
- Monitor for Side Effects: Report any adverse effects to your healthcare provider promptly.
- Avoid Mixing Substances: Do not combine opioids with alcohol or other sedatives unless directed by a physician.
Proper Storage and Disposal
Store opioids in a secure place, out of reach of children and others who might misuse them. Dispose of unused medications properly. Many pharmacies offer take-back programs or mail-back envelopes for safe disposal. (U.S. Food and Drug Administration)
When to Seek Help
If you or someone you know is struggling with opioid use:
- Contact a Healthcare Provider: They can provide guidance and support for tapering off opioids safely.
- Reach Out to Support Services: There are numerous resources available for those dealing with substance use disorders.
- In Case of Overdose: Call emergency services immediately. Naloxone, a medication that can reverse opioid overdose, may be available without a prescription in some areas.(Pain Management CME)
Conclusion
While opioids can be an important tool for managing pain, it's crucial to be aware of their risks and use them responsibly. Always engage in open communication with your healthcare provider about your pain management plan and any concerns you may have.
For more information and resources, visit the Opioid Analgesic REMS Patient Counseling Guide.

